Tbp CLIA Kit for Mouse(Mus musculus) | EIAab.comTbp CLIA Kit for Mouse(Mus musculus)

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Tbp (Gene name),

TATA-box-binding protein (Protein name ), TBP_MOUSE from NCBI database.

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General Annotation

Antigen Annotation

Predicted Eptitope

Vaild Sequence

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Gene name:

Tbp(Tfiid);

Protein name:

TATA-box-binding protein;

Alternative:

TATA-binding factor;TATA sequence-binding protein;Transcription initiation factor TFIID TBP subunit;TATA-box factor;

Organism:

Mouse (Mus musculus).

General Annotation

Sub Unit:

Binds DNA as monomer. Belongs to the TFIID complex together with the TBP-associated factors (TAFs). Component of the transcription factor SL1/TIF-IB complex, composed of TBP and at least TAF1A, TAF1B TAF1C and TAF1D. Association of TBP to form either TFIID or SL1/TIF-IB appears to be mutually exclusive. Interacts with TAF1A, TAF1B and TAF1C. Interacts with TFIIB, NCOA6, DRAP1, DR1 and ELF3. Interacts with SPIB, SNAPC1, SNAPC2 and SNAPC4. Interacts with BRF2. Interacts with UBTF (By similarity). Interacts with UTF1. Interacts with GPBP1. Interacts with SP1 (By similarity). Interacts with CITED2.

Function:

General transcription factor that functions at the core of the DNA-binding multiprotein factor TFIID. Binding of TFIID to the TATA box is the initial transcriptional step of the pre-initiation complex (PIC), playing a role in the activation of eukaryotic genes transcribed by RNA polymerase II. Component of the transcription factor SL1/TIF-IB complex, which is involved in the assembly of the PIC (preinitiation complex) during RNA polymerase I-dependent transcription. The rate of PIC formation probably is primarily dependent on the rate of association of SL1 with the rDNA promoter. SL1 is involved in stabilization of nucleolar transcription factor 1/UBTF on rDNA.

Subcellular Location:

Nucleus

Protein Attributes:

Sequence length:

316

Sequence:

50:

100:

150:

200:

250:

300:

316:

AFENIYPILK | GFRKTT

3D Structure:

N/A

Predicted Eptitope:

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Vaild Sequence:

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Related Databases

KEGG:

mmu:21374

String:

P29037

SMR:

P29037

UniGene:

Mm.244820

Pfam:

PF00352

Uniprot:

P29037

FOR

ELISA Kit for Mouse TATA-box-binding protein

Cat.:

E0360h

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Manual:

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96T

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ELISA Kit for Mouse TATA-box-binding protein

Cat.:

E0360m

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Packing:

96T

ELISA Kit for Mouse TATA-box-binding protein

Cat.:

E0360b

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96T

ELISA Kit for Mouse TATA-box-binding protein

Cat.:

E0360c

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96T

CLIA Kit for Mouse TATA-box-binding protein

Cat.:

U0360h

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MSDS:

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Packing:

96T

CLIA Kit for Mouse TATA-box-binding protein

Cat.:

U0360c

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MSDS:

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Packing:

96T

CLIA Kit for Mouse TATA-box-binding protein

Cat.:

U0360b

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MSDS:

Please sign in first.

Packing:

96T

CLIA Kit for Mouse TATA-box-binding protein

Cat.:

U0360m

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MSDS:

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Packing:

96T

Polyclonal Antibody for Mouse TATA-box-binding protein

Cat.:

P0360Rb-m

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Packing:

40ug/0.2ml

Polyclonal Antibody for Mouse TATA-box-binding protein

Cat.:

P0360Rb-h

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Packing:

40ug/0.2ml

Monoclonal Antibody for Mouse TATA-box-binding protein

Protein for Mouse TATA-box-binding protein

R&D Technical Data

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Precision

For more information, please refer to the manual,Or contact our technical support: tech@eiaab.com.

Recovery

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Linearity

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References

1.

"Striking homology of the 'variable' N-terminal as well as the 'conserved core' domains of the mouse and human TATA-factors (TFIID)."
Tamura T.-A. , Sumita K. , Fujino I. , Aoyama A. , Horikoshi M. , Hoffmann A. , Roeder R.G. , Muramatsu M. , Mikoshiba K.
Nucleic Acids Res.19:3861-3865(1991) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
2.

"Structure of a mammalian TBP (TATA-binding protein) gene: isolation of the mouse TBP genome."
Sumita K. , Makino Y. , Katoh K. , Kashimoto T. , Muramatsu M. , Mikoshiba K. , Tamura T.-A.
Nucleic Acids Res.21:2769-2769(1993) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
3.

"Linkage of TATA-binding protein and proteasome subunit C5 genes in mice and humans reveals synteny conserved between mammals and invertebrates."
Trachtulec Z. , Hamvas R.M. , Forejt J. , Lehrach H.R. , Vincek V. , Klein J.
Genomics44:1-7(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA]
strain: TW18/TW5.
tissue: Testis.
4.

"The transcriptional landscape of the mammalian genome."
Carninci P. , Kasukawa T. , Katayama S. , Gough J. , Frith M.C. , Maeda N. , Oyama R. , Ravasi T. , Lenhard B. , Wells C. , Kodzius R. , Shimokawa K. , Bajic V.B. , Brenner S.E. , Batalov S. , Forrest A.R. , Zavolan M. , Davis M.J. , more...
Science309:1559-1563(2005) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain: C57BL/6J.
tissue: Lung.
5.

"Developmental and cell type-specific regulation of core promoter transcription factors in germ cells of frogs and mice."
Xiao L. , Kim M. , DeJong J.
Gene Expr. Patterns6:409-419(2006) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: TISSUE SPECIFICITY
6.

"The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)."
The MGC Project Team
Genome Res.14:2121-2127(2004) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA]
strain: B5/EGFP transgenic ICR mice.
strain: FVB/N.
tissue: Mammary tumor.
tissue: Trophoblast.
7.

"Promoter structure of the mouse TATA-binding protein (TBP) gene."
Ohbayashi T. , Schmidt E.E. , Makino Y. , Kishimoto T. , Nabeshima Y. , Muramatsu M. , Tamura T.-A.
Biochem. Biophys. Res. Commun.225:275-280(1996) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: NUCLEOTIDE SEQUENCE [MRNA] OF 1-36
8.

"Cloning of murine RNA polymerase I-specific TAF factors: conserved interactions between the subunits of the species-specific transcription initiation factor TIF-IB/SL1."
Heix J. , Zomerdijk J.C.B.M. , Ravanpay A. , Tjian R. , Grummt I.
Proc. Natl. Acad. Sci. U.S.A.94:1733-1738(1997) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH TAF1A; TAF1B AND TAF1C
9.

"UTF1, a novel transcriptional coactivator expressed in pluripotent embryonic stem cells and extra-embryonic cells."
Okuda A. , Fukushima A. , Nishimoto M. , Orimo A. , Yamagishi T. , Nabeshima Y. , Kuro-o M. , Nabeshima Y. , Boon K. , Keaveney M. , Stunnenberg H.G. , Muramatsu M.
EMBO J.17:2019-2032(1998) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH UTF1
10.

"MRG1 binds to the LIM domain of Lhx2 and may function as a coactivator to stimulate glycoprotein hormone alpha-subunit gene expression."
Glenn D.J. , Maurer R.A.
J. Biol. Chem.274:36159-36167(1999) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH CITED2
11.

"The murine G+C-rich promoter binding protein mGPBP is required for promoter-specific transcription."
Hsu L.-C. , Liu S. , Abedinpour F. , Beech R.D. , Lahti J.M. , Kidd V.J. , Greenspan J.A. , Yeung C.-Y.
Mol. Cell. Biol.23:8773-8785(2003) [PubMed] [Europe PMC] [Abstract]

[15/1/25 17:38] Upload to ab completed in less than a minute: 1 file transferred (13.4 Kb/s) Cited for: INTERACTION WITH GPBP1

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